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Coronary artery disease is the most common form of heart disease. Coronary arteries supply the heart muscle with the oxygen and nutrients it needs to function properly. Build-up of plaque, primarily fat and cholesterol, on the inside walls of the coronary arteries slows, or even stops the amount of blood that flows to the heart muscle. When the heart no longer receives enough blood to function properly, part of the heart can die causing a heart attack or even death.